The best audio interface with MIDI ports gives you clean recordings while connecting keyboards, drum machines, controllers, and other hardware without extra adapters. The right model depends on your input count, monitoring needs, computer connection, and workflow.
We compared 10 popular interfaces across sound quality, I/O, MIDI connectivity, ease of use, and value to help you choose a practical setup for recording vocals, instruments, electronic music, and more.
Best 10 Audio Interface with Midi Ports Picks for 2026
Most Versatile Starter
- Five-pin MIDI input and output
- Two combo inputs with 48V phantom power
- Includes recording and music-production software
Best For: Beginners and compact home studios using microphones, instruments, and MIDI gear
Best 4x4 Expansion
- 4-in/4-out USB-C connectivity
- MIDI I/O with hardware monitoring
- LCD screen and loopback support
Best For: Producers, podcasters, and mobile users needing flexible I/O
Best Rugged 2x2 Value
- MIDI I/O with two audio inputs and outputs
- Onyx preamps with 48V phantom power
- Bus-powered and built for everyday use
Best For: Solo musicians recording vocals, instruments, and MIDI parts
Best Compact MOTU Option
- 2-in/2-out USB-C interface
- Two preamps with hardware monitoring
- 24-bit/192kHz recording and 6GB+ content
Best For: Solo musicians and home studios needing a focused two-channel setup
Versatile 4-Input Pick
- Four inputs and four outputs plus MIDI I/O
- 24-bit/192 kHz support with four mic preamps
- Rugged metal chassis and +48V phantom power
Best For: Multi-microphone recording and MIDI-equipped home studios
Modern Two-Channel Choice
- Two mic preamps and two Hi-Z instrument inputs
- Auto Gain, Clip Safe, and Air modes
- 24-bit/192 kHz recording with 120 dB dynamic range
Best For: Solo recording with convenient level-control features
Portable MIDI Value
- Two mic preamps, instrument inputs, and MIDI I/O
- 24-bit/96 kHz recording and playback
- Bus-powered USB design with zero-latency monitoring
Best For: Portable two-channel recording and MIDI hardware setups
Premium Solo Recording
- 120dB dynamic range with 24-bit/192kHz support
- Air modes for vocals and guitars
- Includes a broad recording software bundle
Best For: Solo songwriters recording vocals and guitar
Versatile Budget Recording
- Two combo XLR/line/instrument inputs
- Zero-latency USB/Direct monitoring switch
- Includes MPC Beats production software
Best For: Entry-level recording, podcasting, and streaming
Flexible 2-In/4-Out Recording
- 2-in/4-out design with combo inputs
- 24-bit/192kHz recording capability
- Four zero-latency monitoring modes
Best For: Home studios and livestream setups needing flexible outputs
Most Versatile Starter – Arturia MiniFuse 2
If you need an audio interface with MIDI ports for recording vocals, guitar, synths, or drum machines, the Arturia MiniFuse 2 offers a compact, plug-and-play setup. It combines two combo inputs, balanced outputs, headphone monitoring, USB connectivity, and five-pin MIDI input and output in a portable design.
Best For: Beginners, home studios, guitarists, vocalists, and producers using MIDI synths or controllers.
Pros:
- Includes five-pin MIDI input and output for synths, controllers, and drum machines.
- Two combo mic/instrument/line inputs with 48V phantom power.
- Loopback supports capturing voiceovers alongside in-app or in-game audio.
- Includes Ableton Live Lite, Analog Lab Intro, effects, guitar software, and other creative tools.
Cons:
- Its two-input configuration may be limiting for larger recording sessions.
- The USB hub is rated for 250mA, which may restrict bus-powered accessories.
The MiniFuse 2 is a particularly approachable choice when MIDI connectivity, beginner-friendly software, and flexible recording inputs matter. Its five-year warranty also adds reassurance for a portable interface intended for regular use.
Best 4×4 Expansion – MOTU M4
The MOTU M4 is an audio interface with MIDI ports for musicians, podcasters, and producers who need more routing flexibility than a basic two-channel model. Its 4-in/4-out USB-C design includes two microphone preamps, hardware monitoring, an LCD screen, and loopback functionality.
Best For: Recording and mixing setups that need four inputs and four outputs, low-latency monitoring, or podcast loopback.
Pros:
- Provides 4-in/4-out USB-C connectivity for expanded routing.
- Includes MIDI I/O and low-latency hardware monitoring.
- LCD screen helps with monitoring recording levels.
- Supports Mac, PC, and iOS devices and includes more than 6GB of free content.
Cons:
- Its larger I/O layout may be more than a simple two-input recording setup requires.
- The supplied notes do not specify the exact number of MIDI ports or included MIDI cables.
Choose the M4 when additional analog I/O and flexible monitoring are more important than keeping the interface as small and simple as possible. Loopback and iOS compatibility also make it useful for content-focused workflows.
Best Rugged 2×2 Value – Mackie Onyx Producer 2-2
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonFor shoppers seeking an audio interface with MIDI ports in a straightforward 2×2 format, the Mackie Onyx Producer 2-2 pairs MIDI I/O with two Onyx microphone preamps. Its combo inputs accept microphone, line, and Hi-Z sources, while bus-powered USB operation supports mobile recording without a separate power adapter.
Best For: Musicians who want MIDI connectivity, direct monitoring, and a durable interface for two-channel recording.
Pros:
- Includes MIDI I/O alongside 2-in/2-out audio recording.
- Two Onyx mic preamps provide 48V phantom power for condenser microphones.
- Combo inputs accept mic, line, and Hi-Z instrument sources.
- Offers zero-latency direct monitoring and bus-powered USB operation.
Cons:
- Two inputs and two outputs provide less expansion than a 4×4 interface.
- USB 2.0 is older than the USB-C connectivity found on some alternatives.
- The listed warranty is one year.
The Onyx Producer 2-2 is a practical fit for solo recording, especially if you value Hi-Z instrument support, direct monitoring, and a rugged build. It keeps the workflow focused while still accommodating MIDI equipment.
Best Compact MOTU Option – MOTU M2
The MOTU M2 is a compact audio interface with MIDI ports aimed at users who want a focused 2-in/2-out recording setup. It offers USB-C connectivity, two preamps, hardware monitoring, 24-bit/192kHz operation, and compatibility with macOS, Windows, and iOS.
Best For: Solo musicians and home-studio users who need two preamps, high-resolution recording, and a compact USB-C interface.
Pros:
- Provides 2-in/2-out USB-C audio connectivity.
- Includes two microphone preamps and hardware monitoring.
- Supports 24-bit/192kHz recording.
- Works with macOS, Windows, and iOS and includes more than 6GB of free content.
Cons:
- The supplied notes do not detail the exact MIDI port configuration.
- Two inputs and two outputs may not suit larger ensembles or complex routing.
- The listed operating-system details emphasize Windows, while broader compatibility is described separately.
The M2 makes sense for a streamlined two-channel setup where USB-C, hardware monitoring, and high-resolution recording take priority. Confirm the specific MIDI connections you need before buying if MIDI integration is central to your setup.
Versatile 4-Input Pick – U-PHORIA UMC404HD
For musicians needing an audio interface with MIDI ports and room for several sources, the Behringer U-PHORIA UMC404HD offers four inputs, four outputs, and dedicated MIDI I/O. Its 24-bit/192 kHz support, four MIDAS-designed mic preamps, and rugged metal chassis make it a practical choice for more involved home-studio setups.
Best For: Recording multiple microphones or instruments while connecting MIDI hardware.
Pros:
- Four-input, four-output USB interface with MIDI I/O
- 24-bit/192 kHz recording and playback support
- Four mic preamps with +48V phantom power
- Impact-resistant metal chassis
Cons:
- Larger and heavier than the two-channel options here
- Its four-input capacity may be more than a basic setup needs
The UMC404HD is the strongest fit when expandability matters. It combines substantial connectivity with high-resolution recording and balanced studio features, although a smaller interface may be more convenient for simple, portable recording.
Modern Two-Channel Choice – Scarlett 2i2 4th Gen
The Focusrite Scarlett 2i2 4th Gen is a compact option for buyers who want an audio interface with MIDI ports alongside straightforward microphone and instrument recording. It provides two mic preamps, two Hi-Z inputs, 24-bit/192 kHz operation, and helpful Auto Gain and Clip Safe features.
Best For: Solo musicians and small recording setups that prioritize easy level control and polished sound.
Pros:
- Two mic preamps and two Hi-Z instrument inputs
- 120 dB dynamic range with 24-bit/192 kHz support
- Auto Gain and Clip Safe help manage recording levels
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion
Cons:
- Only two audio channels for simultaneous recording
- The supplied notes do not specify the MIDI I/O configuration
The Scarlett 2i2 is appealing for creators who want an accessible two-channel interface with modern recording assistance and bundled software. Verify the exact MIDI-port requirements before buying if hardware MIDI connectivity is essential to your setup.
Portable MIDI Value – AudioBox 96 25th Anniversary
The PreSonus AudioBox 96 is a practical budget-minded audio interface with MIDI ports for personal and portable recording. Its two Class-A mic preamps, instrument inputs, bus-powered USB design, and zero-latency mixer control cover the essentials for a compact studio.
Best For: Mobile-friendly two-channel recording with microphones, instruments, and MIDI hardware.
Pros:
- Two mic preamps, two instrument inputs, and MIDI I/O
- 24-bit/96 kHz studio-grade converters
- USB bus-powered design needs no additional power supply
- Includes Studio One Artist, Ableton Live Lite, and Studio Magic Plug-In suite
Cons:
- Maximum sample rate is lower than the 192 kHz alternatives
- Two-channel design limits simultaneous sources
- One-year manufacturer warranty
The AudioBox 96 makes sense when portability, MIDI connectivity, and included software matter more than maximum sample rate. It is a straightforward option for home recording, rehearsal capture, and compact mobile rigs.
Premium Solo Recording – Scarlett Solo 4th Gen
The Focusrite Scarlett Solo 4th Gen is a compact audio interface with midi ports alternative for solo creators who primarily need microphone and instrument connections. Its 120dB dynamic range, 24-bit/192kHz support, and Air modes target polished vocal and guitar recordings, while USB-C connectivity supports computer and iPad workflows.
Best For: Songwriters, vocalists, and guitarists recording one microphone and one instrument at a time.
Pros:
- Studio-oriented 120dB dynamic range and up to 192kHz recording.
- Air modes add presence and harmonic drive to vocals and guitars.
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion.
- Works with Mac, Windows, and iPad systems.
Cons:
- Provides one XLR microphone preamp and one Hi-Z instrument input.
- The supplied specifications list USB connectivity rather than MIDI ports.
The Solo 4th Gen is a strong choice when recording quality and included software matter more than extensive I/O. If your setup requires traditional MIDI connections, verify your equipment needs before buying.
Versatile Budget Recording – M-Track Duo USB Interface
The M-AUDIO M-Track Duo is a practical audio interface with midi ports alternative for recording, podcasting, and streaming on a Mac or PC. Two combo XLR/line/instrument inputs, phantom power, and direct monitoring make it flexible for microphones, guitars, and line-level sources.
Best For: Beginners, podcasters, streamers, and musicians who need two inputs at an accessible price.
Pros:
- Two combo inputs accept microphone, line, and instrument signals.
- Phantom power supports compatible condenser microphones.
- USB/Direct switching enables zero-latency monitoring.
- Includes MPC Beats and supports Mac, Windows, iOS, and Android systems.
Cons:
- Recording resolution is limited to 48kHz.
- The supplied specifications do not list MIDI ports.
Choose the M-Track Duo when straightforward two-channel recording and monitoring are the priority. Its broad device compatibility is useful for simple mobile and desktop setups, but dedicated MIDI connectivity is not identified in the supplied specifications.
Flexible 2-In/4-Out Recording – BlueAVS AR013 USB Interface
The BlueAVS AR013 is a flexible audio interface with midi ports alternative that combines two combo inputs with four outputs for recording, streaming, and podcasting. It supports 24-bit/192kHz audio, USB-C computer connectivity, independent 48V phantom power, and multiple zero-latency monitoring modes.
Best For: Home studios, livestreamers, and creators who need flexible monitoring and multiple balanced outputs.
Pros:
- Two XLR/TRS combo inputs and four outputs support varied studio setups.
- Records at up to 24-bit/192kHz across several sample rates.
- Offers Off, Mono, Crossfeed, and Stereo monitoring modes.
- Includes phantom power and PAD switches for condenser microphones and louder sources.
Cons:
- Its supplied specifications do not list MIDI ports.
- Limited to two audio input channels.
- Includes a one-year limited manufacturer coverage period.
The AR013 stands out for creators who value output flexibility and monitoring control alongside high-resolution recording. It is a capable USB-C option for modern computer-based workflows, but buyers specifically seeking MIDI ports should confirm compatibility separately.
How We Picked the Best Audio Interface with Midi Ports
We focused on interfaces that provide useful connections for both computer-based recording and external MIDI hardware. Our comparison considers preamp quality, converter specifications, input and output counts, MIDI implementation, headphone monitoring, phantom power, latency features, build quality, software compatibility, and overall value.
Not every model in this roundup is equally suited to the same user. Some are compact two-channel interfaces for solo recording, while others offer four inputs and outputs for larger recording sessions or more elaborate hardware rigs. We also considered whether the controls and connections are approachable for beginners without limiting experienced producers.
Quick Comparison
- Best for flexible home studios: Look for four inputs and outputs, dedicated MIDI connections, and dependable direct monitoring.
- Best for solo creators: Two-input interfaces are smaller, simpler, and usually sufficient for one microphone and one instrument.
- Best for keyboards and controllers: Confirm that the unit has standard five-pin MIDI In and Out if you need traditional hardware compatibility.
- Best for low-cost recording: Prioritize clean preamps, phantom power, and reliable headphone output over headline sample-rate figures.
Key Buying Factors for an Audio Interface with Midi Ports
Inputs and Outputs
Count the sources you expect to record at the same time. Two inputs suit vocals, guitar, stereo keyboards, and basic streaming. Four or more inputs provide more flexibility for drums, multiple performers, and external hardware. Also check whether outputs support multiple monitor mixes, speakers, or outboard effects.
MIDI Connections
A standard MIDI interface connection is useful for synthesizers, drum machines, and older controllers. Check whether the product includes MIDI In, MIDI Out, or both, and distinguish those ports from USB MIDI support. If your setup depends on several hardware instruments, you may still need a dedicated MIDI hub.
Audio Quality and Monitoring
Higher sample-rate and bit-depth ratings can be useful, but practical performance matters more. Look for quiet preamps, enough gain for your microphones, 48V phantom power for condenser microphones, and direct monitoring or low-latency software monitoring.
Computer and Power Requirements
Confirm USB-C or USB-A compatibility, driver support, and whether the interface is bus-powered. Some microphones and headphones require substantial power, so review the headphone amplifier and total power requirements before buying.
Who Should Buy Which Audio Interface with Midi Ports?
Choose a compact two-input model if you record alone, produce beats, stream, or need a portable interface for a laptop. Choose a four-channel model if you record several sources at once or use multiple synthesizers and drum machines. Choose a model with strong metering and loopback features for streaming, online lessons, or content creation. Finally, prioritize established driver support and straightforward controls if this is your first interface; a simple setup is easier to use consistently than one with features you do not need.